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Structure of Human Complement C8, a Precursor to Membrane Attack
Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021121/ https://ncbi.nlm.nih.gov/pubmed/21073882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.031 |
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