Structure of Human Complement C8, a Precursor to Membrane Attack

Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...

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Detalles Bibliográficos
Autores principales: Bubeck, Doryen, Roversi, Pietro, Donev, Rossen, Morgan, B. Paul, Llorca, Oscar, Lea, Susan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2011
Materias:
Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021121/
https://ncbi.nlm.nih.gov/pubmed/21073882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.031
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