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CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers
The membrane attack complex (MAC) is one of the immune system’s first responders. Complement proteins assemble on target membranes to form pores that lyse pathogens and impact tissue homeostasis of self-cells. How MAC disrupts the membrane barrier remains unclear. Here we use electron cryo-microscop...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294249/ https://ncbi.nlm.nih.gov/pubmed/30552328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07653-5 |
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