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Advances in cryoEM and its impact on β-pore forming proteins
Deployed by both hosts and pathogens, β-pore-forming proteins (β-PFPs) rupture membranes and lyse target cells. Soluble protein monomers oligomerize on the lipid bilayer where they undergo dramatic structural rearrangements, resulting in a transmembrane β-barrel pore. Advances in electron cryo-micro...
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| Опубликовано в: : | Curr Opin Struct Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier Science
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6302071/ https://ncbi.nlm.nih.gov/pubmed/30125772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.07.010 |
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