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Advances in cryoEM and its impact on β-pore forming proteins

Deployed by both hosts and pathogens, β-pore-forming proteins (β-PFPs) rupture membranes and lyse target cells. Soluble protein monomers oligomerize on the lipid bilayer where they undergo dramatic structural rearrangements, resulting in a transmembrane β-barrel pore. Advances in electron cryo-micro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Struct Biol
Main Authors: Boyd, Courtney M, Bubeck, Doryen
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302071/
https://ncbi.nlm.nih.gov/pubmed/30125772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.07.010
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