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Soluble Membrane Attack Complex: Biochemistry and Immunobiology

The soluble membrane attack complex (sMAC, a.k.a., sC5b-9 or TCC) is generated on activation of complement and contains the complement proteins C5b, C6, C7, C8, C9 together with the regulatory proteins clusterin and/or vitronectin. sMAC is a member of the MACPF/cholesterol-dependent-cytolysin superf...

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Publicat a:Front Immunol
Autors principals: Barnum, Scott R., Bubeck, Doryen, Schein, Theresa N.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683570/
https://ncbi.nlm.nih.gov/pubmed/33240274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585108
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