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Packing a punch: The mechanism of pore formation by cholesterol dependent cytolysins and Membrane Attack/Perforin-like proteins

The bacterial cholesterol dependent cytolysins (CDCs) and membrane attack complex/perforin-like proteins (MACPF) represent two major branches of a large, exceptionally diverged superfamily. Most characterized CDC/MACPF proteins form large pores that function in immunity, venoms, and pathogenesis. Ex...

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Detalhes bibliográficos
Main Authors: Dunstone, Michelle A., Tweten, Rodney K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383384/
https://ncbi.nlm.nih.gov/pubmed/22658510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.04.008
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