Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors and effectors in immune defence. Upon binding to the membrane, they convert from the soluble monomeric form to oligome...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Leung, Carl, Dudkina, Natalya V, Lukoyanova, Natalya, Hodel, Adrian W, Farabella, Irene, Pandurangan, Arun P, Jahan, Nasrin, Pires Damaso, Mafalda, Osmanović, Dino, Reboul, Cyril F, Dunstone, Michelle A, Andrew, Peter W, Lonnen, Rana, Topf, Maya, Saibil, Helen R, Hoogenboom, Bart W
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2014
Teme:
Biophysics and Structural Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381977/
https://ncbi.nlm.nih.gov/pubmed/25457051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04247
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