Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors and effectors in immune defence. Upon binding to the membrane, they convert from the soluble monomeric form to oligome...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Leung, Carl, Dudkina, Natalya V, Lukoyanova, Natalya, Hodel, Adrian W, Farabella, Irene, Pandurangan, Arun P, Jahan, Nasrin, Pires Damaso, Mafalda, Osmanović, Dino, Reboul, Cyril F, Dunstone, Michelle A, Andrew, Peter W, Lonnen, Rana, Topf, Maya, Saibil, Helen R, Hoogenboom, Bart W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381977/
https://ncbi.nlm.nih.gov/pubmed/25457051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04247
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