Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin

Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors and effectors in immune defence. Upon binding to the membrane, they convert from the soluble monomeric form to oligome...

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Vydáno v:eLife
Hlavní autoři: Leung, Carl, Dudkina, Natalya V, Lukoyanova, Natalya, Hodel, Adrian W, Farabella, Irene, Pandurangan, Arun P, Jahan, Nasrin, Pires Damaso, Mafalda, Osmanović, Dino, Reboul, Cyril F, Dunstone, Michelle A, Andrew, Peter W, Lonnen, Rana, Topf, Maya, Saibil, Helen R, Hoogenboom, Bart W
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
Biophysics and Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381977/
https://ncbi.nlm.nih.gov/pubmed/25457051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04247
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