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Model Inspired by Nuclear Pore Complex Suggests Possible Roles for Nuclear Transport Receptors in Determining Its Structure

Nuclear transport receptors (NTRs) mediate nucleocytoplasmic transport via their affinity for unstructured proteins (polymers) in the nuclear pore complex (NPC). Here, we have modeled the effect of NTRs on polymeric structure in the nanopore confinement of the NPC central conduit. The model explicit...

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Bibliografiske detaljer
Main Authors: Osmanović, Dino, Ford, Ian J., Hoogenboom, Bart W.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882460/
https://ncbi.nlm.nih.gov/pubmed/24359750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.013
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