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Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes
The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ~5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC(1). Whilst the structure an...
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| 出版年: | Nat Nanotechnol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286247/ https://ncbi.nlm.nih.gov/pubmed/25420031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2014.262 |
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