Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes

The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ~5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC(1). Whilst the structure an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Nanotechnol
Egile Nagusiak: Bestembayeva, Aizhan, Kramer, Armin, Labokha, Aksana A., Osmanović, Dino, Liashkovich, Ivan, Orlova, Elena V., Ford, Ian J., Charras, Guillaume, Fassati, Ariberto, Hoogenboom, Bart W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286247/
https://ncbi.nlm.nih.gov/pubmed/25420031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2014.262
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