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Screening of 71 P. multocida Proteins for Protective Efficacy in a Fowl Cholera Infection Model and Characterization of the Protective Antigen PlpE

BACKGROUND: There is a strong need for a recombinant subunit vaccine against fowl cholera. We used a reverse vaccinology approach to identify putative secreted or cell surface associated P. multocida proteins that may represent potential vaccine candidate antigens. PRINCIPAL FINDINGS: A high-through...

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Detalhes bibliográficos
Main Authors: Hatfaludi, Tamás, Al-Hasani, Keith, Gong, Lan, Boyce, John D., Ford, Mark, Wilkie, Ian W., Quinsey, Noelene, Dunstone, Michelle A., Hoke, David E., Adler, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390355/
https://ncbi.nlm.nih.gov/pubmed/22792202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039973
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