The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases

Por Clark, Andrew R., Dean, Jonathan L.E.
Publicado no Biochem Soc Trans (2016)

Identification of a novel AU-rich-element-binding protein which is related to AUF1.

Por Dean, Jonathan L E, Sully, Gareth, Wait, Robin, Rawlinson, Lesley, Clark, Andrew R, Saklatvala, Jeremy
Publicado em 2002

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Por Dean, Jonathan L. E., Wait, Robin, Mahtani, Kamal R., Sully, Gareth, Clark, Andrew R., Saklatvala, Jeremy
Publicado em 2001

Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Por Mahtani, Kamal R., Brook, Matthew, Dean, Jonathan L. E., Sully, Gareth, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2001

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Por Dean, Jonathan L. E., Wait, Robin, Mahtani, Kamal R., Sully, Gareth, Clark, Andrew R., Saklatvala, Jeremy
Publicado em 2005

MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment

Por Marchese, Francesco P., Aubareda, Anna, Tudor, Corina, Saklatvala, Jeremy, Clark, Andrew R., Dean, Jonathan L. E.
Publicado em 2010

The major transition state in folding need not involve the immobilization of side chains

Por Staniforth, Rosemary A., Dean, Jonathan L. E., Zhong, Qi, Zerovnik, Eva, Clarke, Anthony R., Waltho, Jonathan P.
Publicado em 2000

Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degr...

Por Sully, Gareth, Dean, Jonathan L E, Wait, Robin, Rawlinson, Lesley, Santalucia, Tomas, Saklatvala, Jeremy, Clark, Andrew R
Publicado em 2004

p38 mitogen-activated protein kinase inhibits tristetraprolin-directed decay of the mRNA of the anti-inflammatory cytokine interleukin-10

Por Tudor, Corina, Hitti, Edward, Rawlinson, Lesley, Blackshear, Perry J., Gaestel, Matthias, Clark, Andrew R., Saklatvala, Jeremy, Dean, Jonathan L.E.
Publicado no FEBS Lett (2009)

Heat Shock Protein B1-Deficient Mice Display Impaired Wound Healing

Por Crowe, Jonathan, Aubareda, Anna, McNamee, Kay, Przybycien, Paulina M., Lu, Xin, Williams, Richard O., Bou-Gharios, George, Saklatvala, Jeremy, Dean, Jonathan L. E.
Publicado em 2013

Heat shock protein‐27 and sex‐selective regulation of muscarinic and proteinase‐activated receptor 2‐mediated vasodilatation: differential sensitivity to endothelial NOS inhibition...

Por Pulakazhi Venu, Vivek Krishna, Saifeddine, Mahmoud, Mihara, Koichiro, El‐Daly, Mahmoud, Belke, Darrell, Dean, Jonathan L E, O'Brien, Edward R, Hirota, Simon A, Hollenberg, Morley D
Publicado no Br J Pharmacol (2018)

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation

Por Brook, Matthew, Tomlinson, Gareth H., Miles, Katherine, Smith, Richard W. P., Rossi, Adriano G., Hiemstra, Pieter S., van ’t Wout, Emily F. A., Dean, Jonathan L. E., Gray, Nicola K., Lu, Wuyuan, Gray, Mohini
Publicado no Proc Natl Acad Sci U S A (2016)

MSK1 and MSK2 Inhibit Lipopolysaccharide-Induced Prostaglandin Production via an Interleukin-10 Feedback Loop

Por MacKenzie, Kirsty F., Van Den Bosch, Mirjam W. M., Naqvi, Shaista, Elcombe, Suzanne E., McGuire, Victoria A., Reith, Alastair D., Blackshear, Perry J., Dean, Jonathan L. E., Arthur, J. Simon C.
Publicado em 2013

Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Por McGuire, Victoria A., Gray, Alexander, Monk, Claire E., Santos, Susana G., Lee, Keunwook, Aubareda, Anna, Crowe, Jonathan, Ronkina, Natalia, Schwermann, Jessica, Batty, Ian H., Leslie, Nick R., Dean, Jonathan L. E., O'Keefe, Stephen J., Boothby, Mark, Gaestel, Matthias, Arthur, J. Simon C.
Publicado em 2013