The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Posttranscriptional regulation is important for tumor necrosis factor alpha (TNF-α) expression in monocytes and macrophages, and an AU-rich element (ARE) in the 3′ untranslated region (UTR) of TNF-α mRNA is implicated in control of its translation and mRNA stability. Regulation of mRNA turnover is t...

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Bibliografiska uppgifter
Huvudupphovsmän: Dean, Jonathan L. E., Wait, Robin, Mahtani, Kamal R., Sully, Gareth, Clark, Andrew R., Saklatvala, Jeremy
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC86664/
https://ncbi.nlm.nih.gov/pubmed/11154260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.721-730.2001
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