Dexamethasone Causes Sustained Expression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase 1 and Phosphatase-Mediated Inhibition of MAPK p38

The stress-activated protein kinase p38 stabilizes a number of mRNAs encoding inflammatory mediators, such as cyclooxygenase 2 (Cox-2). In HeLa cells the anti-inflammatory glucocorticoid dexamethasone destabilizes Cox-2 mRNA by inhibiting p38 function. Here we demonstrate that this effect is phospha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lasa, Marina, Abraham, Sonya M., Boucheron, Christine, Saklatvala, Jeremy, Clark, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134716/
https://ncbi.nlm.nih.gov/pubmed/12391149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7802-7811.2002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados