Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Signal transduction pathways regulate gene expression in part by modulating the stability of specific mRNAs. For example, the mitogen-activated protein kinase (MAPK) p38 pathway mediates stabilization of tumor necrosis factor alpha (TNF-α) mRNA in myeloid cells stimulated with bacterial lipopolysacc...

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Bibliographische Detailangaben
Hauptverfasser: Mahtani, Kamal R., Brook, Matthew, Dean, Jonathan L. E., Sully, Gareth, Saklatvala, Jeremy, Clark, Andrew R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC99793/
https://ncbi.nlm.nih.gov/pubmed/11533235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.6461-6469.2001
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