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Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Signal transduction pathways regulate gene expression in part by modulating the stability of specific mRNAs. For example, the mitogen-activated protein kinase (MAPK) p38 pathway mediates stabilization of tumor necrosis factor alpha (TNF-α) mRNA in myeloid cells stimulated with bacterial lipopolysacc...

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Publicado no:Mol Cell Biol
Principais autores: Mahtani, Kamal R., Brook, Matthew, Dean, Jonathan L. E., Sully, Gareth, Saklatvala, Jeremy, Clark, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2001
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533235/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.6461-6469.2001
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