The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look

Por Clark, Andrew R, Dean, Jonathan LE
Publicado em 2012

The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases

Por Clark, Andrew R., Dean, Jonathan L.E.
Publicado no Biochem Soc Trans (2016)

Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38

Por Lasa, Marina, Brook, Matthew, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2001

Role of Dual Specificity Phosphatases in Biological Responses to Glucocorticoids

Por Clark, Andrew R., Martins, Joana R. S., Tchen, Carmen R.
Publicado em 2008

Dexamethasone Causes Sustained Expression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase 1 and Phosphatase-Mediated Inhibition of MAPK p38

Por Lasa, Marina, Abraham, Sonya M., Boucheron, Christine, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2002

The role of microRNAs in glucocorticoid action

Por Clayton, Sally A., Jones, Simon W., Kurowska-Stolarska, Mariola, Clark, Andrew R.
Publicado no J Biol Chem (2018)

Mkp1 Is a c-Jun Target Gene That Antagonizes JNK-Dependent Apoptosis in Sympathetic Neurons

Por Kristiansen, Mark, Hughes, Rosie, Patel, Pritika, Jacques, Thomas S., Clark, Andrew R., Ham, Jonathan
Publicado em 2010

Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1

Por Joanny, Eugénie, Ding, Qize, Gong, Leyi, Kong, Philip, Saklatvala, Jeremy, Clark, Andrew R
Publicado em 2012

Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade

Por Lasa, Marina, Mahtani, Kamal R., Finch, Andrew, Brewer, Gary, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2000

Identification of a novel AU-rich-element-binding protein which is related to AUF1.

Por Dean, Jonathan L E, Sully, Gareth, Wait, Robin, Rawlinson, Lesley, Clark, Andrew R, Saklatvala, Jeremy
Publicado em 2002

Glucocorticoid Regulation of Mouse and Human Dual Specificity Phosphatase 1 (DUSP1) Genes: UNUSUAL CIS-ACTING ELEMENTS AND UNEXPECTED EVOLUTIONARY DIVERGENCE

Por Tchen, Carmen R., Martins, Joana R. S., Paktiawal, Nasren, Perelli, Roberta, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2010

IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages

Por Smallie, Tim, Ricchetti, Giuseppe, Horwood, Nicole J., Feldmann, Marc, Clark, Andrew R., Williams, Lynn M.
Publicado em 2010

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Por Dean, Jonathan L. E., Wait, Robin, Mahtani, Kamal R., Sully, Gareth, Clark, Andrew R., Saklatvala, Jeremy
Publicado em 2001

Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

Por Mahtani, Kamal R., Brook, Matthew, Dean, Jonathan L. E., Sully, Gareth, Saklatvala, Jeremy, Clark, Andrew R.
Publicado em 2001

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Por Dean, Jonathan L. E., Wait, Robin, Mahtani, Kamal R., Sully, Gareth, Clark, Andrew R., Saklatvala, Jeremy
Publicado em 2005

MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment

Por Marchese, Francesco P., Aubareda, Anna, Tudor, Corina, Saklatvala, Jeremy, Clark, Andrew R., Dean, Jonathan L. E.
Publicado em 2010

Strain dependent differences in glucocorticoid-induced bone loss between C57BL/6J and CD-1 mice

Por Ersek, Adel, Santo, Ana I. Espirito, Vattakuzhi, Youridies, George, Saumya, Clark, Andrew R., Horwood, Nicole J.
Publicado no Sci Rep (2016)

Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degr...

Por Sully, Gareth, Dean, Jonathan L E, Wait, Robin, Rawlinson, Lesley, Santalucia, Tomas, Saklatvala, Jeremy, Clark, Andrew R
Publicado em 2004

Dual Specificity Phosphatase 1 Regulates Human Inducible Nitric Oxide Synthase Expression by p38 MAP Kinase

Por Turpeinen, Tuija, Nieminen, Riina, Taimi, Ville, Heittola, Taina, Sareila, Outi, Clark, Andrew R., Moilanen, Eeva, Korhonen, Riku
Publicado em 2011

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome

Por Haneklaus, Moritz, O'Neil, John D., Clark, Andrew R., Masters, Seth L., O'Neill, Luke A. J.
Publicado no J Biol Chem (2017)