MSK1 and MSK2 Inhibit Lipopolysaccharide-Induced Prostaglandin Production via an Interleukin-10 Feedback Loop

Prostaglandin production is catalyzed by cyclooxygenase 2 (cox-2). We demonstrate here that MSK1 and MSK2 (MSK1/2) can exert control on the induction of cox-2 mRNA by Toll-like receptor (TLR) agonists. In the initial phase of cox-2 induction, MSK1/2 knockout macrophages confirmed a role for MSK in t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: MacKenzie, Kirsty F., Van Den Bosch, Mirjam W. M., Naqvi, Shaista, Elcombe, Suzanne E., McGuire, Victoria A., Reith, Alastair D., Blackshear, Perry J., Dean, Jonathan L. E., Arthur, J. Simon C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624268/
https://ncbi.nlm.nih.gov/pubmed/23382072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01690-12
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak