Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases

Autor DeBalsi, Karen L., Hoff, Kirsten E., Copeland, William C.
Vydáno v Ageing Res Rev (2016)

Synergistic Effects of the in cis T251I and P587L Mitochondrial DNA Polymerase γ Disease Mutations

Autor DeBalsi, Karen L., Longley, Matthew J., Hoff, Kirsten E., Copeland, William C.
Vydáno v J Biol Chem (2017)

POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity

Autor Young, Matthew J., Humble, Margaret M., DeBalsi, Karen L., Sun, Kathie Y., Copeland, William C.
Vydáno v Hum Mol Genet (2015)

Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome

Autor Hoff, Kirsten E., DeBalsi, Karen L., Sanchez-Quintero, Maria J., Longley, Matthew J., Hirano, Michio, Naini, Ali B., Copeland, William C.
Vydáno v PLoS One (2018)

Obesity and lipid stress inhibit carnitine acetyltransferase activity

Autor Seiler, Sarah E., Martin, Ola J., Noland, Robert C., Slentz, Dorothy H., DeBalsi, Karen L., Ilkayeva, Olga R., An, Jie, Newgard, Christopher B., Koves, Timothy R., Muoio, Deborah M.
Vydáno 2014

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

Autor Wong, Kari E., Mikus, Catherine R., Slentz, Dorothy H., Seiler, Sarah E., DeBalsi, Karen L., Ilkayeva, Olga R., Crain, Karen I., Kinter, Michael T., Kien, C. Lawrence, Stevens, Robert D., Muoio, Deborah M.
Vydáno v Diabetes (2015)

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Autor Koves, Timothy R., Sparks, Lauren M., Kovalik, J. P., Mosedale, Merrie, Arumugam, Ramamani, DeBalsi, Karen L., Everingham, Karen, Thorne, Leigh, Phielix, Esther, Meex, Ruth C., Kien, C. Lawrence, Hesselink, Matthijs K. C., Schrauwen, Patrick, Muoio, Deborah M.
Vydáno 2013

Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue During Exercise

Autor Seiler, Sarah E., Koves, Timothy R., Gooding, Jessica R., Wong, Kari E., Stevens, Robert S., Ilkayeva, Olga R., Wittmann, April H., DeBalsi, Karen L., Davies, Michael N., Lindeboom, Lucas, Schrauwen, Patrick, Schrauwen-Hinderling, Vera B., Muoio, Deborah M.
Vydáno v Cell Metab (2015)

Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle

Autor DeBalsi, Karen L., Wong, Kari E., Koves, Timothy R., Slentz, Dorothy H., Seiler, Sarah E., Wittmann, April H., Ilkayeva, Olga R., Stevens, Robert D., Perry, Christopher G. R., Lark, Daniel S., Hui, Simon T., Szweda, Luke, Neufer, P. Darrell, Muoio, Deborah M.
Vydáno 2014

Muscle-specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility

Autor Muoio, Deborah M., Noland, Robert C., Kovalik, Jean-Paul, Seiler, Sarah E., Davies, Michael N., DeBalsi, Karen L., Ilkayeva, Olga R., Stevens, Robert D., Kheterpal, Indu, Zhang, Jingying, Covington, Jeffrey D., Bajpeyi, Sudip, Ravussin, Eric, Kraus, William, Koves, Timothy R., Mynatt, Randall L.
Vydáno 2012