Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

This study used mice with muscle-specific overexpression of PGC-1α, a transcriptional coactivator that promotes mitochondrial biogenesis, to determine whether increased oxidative potential facilitates metabolic improvements in response to lifestyle modification. MCK-PGC1α mice and nontransgenic (NT)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Wong, Kari E., Mikus, Catherine R., Slentz, Dorothy H., Seiler, Sarah E., DeBalsi, Karen L., Ilkayeva, Olga R., Crain, Karen I., Kinter, Michael T., Kien, C. Lawrence, Stevens, Robert D., Muoio, Deborah M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407850/
https://ncbi.nlm.nih.gov/pubmed/25422105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0827
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados