Muscle-specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility

The concept of “metabolic inflexibility” was first introduced to describe the failure of insulin resistant human subjects to appropriately adjust mitochondrial fuel selection in response to nutritional cues. This phenomenon has since gained increasing recognition as a core component of the metabolic...

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Main Authors: Muoio, Deborah M., Noland, Robert C., Kovalik, Jean-Paul, Seiler, Sarah E., Davies, Michael N., DeBalsi, Karen L., Ilkayeva, Olga R., Stevens, Robert D., Kheterpal, Indu, Zhang, Jingying, Covington, Jeffrey D., Bajpeyi, Sudip, Ravussin, Eric, Kraus, William, Koves, Timothy R., Mynatt, Randall L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348515/
https://ncbi.nlm.nih.gov/pubmed/22560225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.04.005
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