Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis

Proximal tubular epithelial cells are highly energy demanding. Their energy need is covered mostly from mitochondrial fatty acid oxidation. Whether derailments in fatty acid metabolism and mitochondrial dysfunction are forerunners of tubular damage has been suggested but is not entirely clear. Here...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Kruger, Claudia, Nguyen, Trang-Tiffany, Breaux, Chelsea, Guillory, Alana, Mangelli, Margaret, Fridianto, Kevin T., Kovalik, Jean-Paul, Burk, David H., Noland, Robert C., Mynatt, Randall, Stadler, Krisztian
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425873/
https://ncbi.nlm.nih.gov/pubmed/30728184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0090
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