Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis

Proximal tubular epithelial cells are highly energy demanding. Their energy need is covered mostly from mitochondrial fatty acid oxidation. Whether derailments in fatty acid metabolism and mitochondrial dysfunction are forerunners of tubular damage has been suggested but is not entirely clear. Here...

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Vydáno v:Diabetes
Hlavní autoři: Kruger, Claudia, Nguyen, Trang-Tiffany, Breaux, Chelsea, Guillory, Alana, Mangelli, Margaret, Fridianto, Kevin T., Kovalik, Jean-Paul, Burk, David H., Noland, Robert C., Mynatt, Randall, Stadler, Krisztian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2019
Témata:
Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425873/
https://ncbi.nlm.nih.gov/pubmed/30728184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0090
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