Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis

Proximal tubular epithelial cells are highly energy demanding. Their energy need is covered mostly from mitochondrial fatty acid oxidation. Whether derailments in fatty acid metabolism and mitochondrial dysfunction are forerunners of tubular damage has been suggested but is not entirely clear. Here...

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Bibliografische gegevens
Gepubliceerd in:Diabetes
Hoofdauteurs: Kruger, Claudia, Nguyen, Trang-Tiffany, Breaux, Chelsea, Guillory, Alana, Mangelli, Margaret, Fridianto, Kevin T., Kovalik, Jean-Paul, Burk, David H., Noland, Robert C., Mynatt, Randall, Stadler, Krisztian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2019
Onderwerpen:
Complications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425873/
https://ncbi.nlm.nih.gov/pubmed/30728184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0090
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