DNA2 Resolves Expanding Flap in Mitochondrial Base Excision Repair

Por Copeland, William C., Longley, Matthew J.
Publicado em 2008

Mitochondrial genome maintenance in health and disease

Por Copeland, William C., Longley, Matthew J.
Publicado em 2014

Analysis of Translesion DNA Synthesis by the Mitochondrial DNA Polymerase γ

Por Copeland, William C., Kasiviswanathan, Rajesh, Longley, Matthew J.
Publicado no Methods Mol Biol (2016)

Preparation of Human Mitochondrial Single-Stranded DNA Binding Protein

Por Longley, Matthew J., Smith, Leslie A., Copeland, William C.
Publicado em 2009

Modulation of the W748S mutation in DNA polymerase γ by the E1143G polymorphism in mitochondrial disorders

Por Chan, Sherine S.L., Longley, Matthew J., Copeland, William C.
Publicado em 2006

Disease Mutations in the Human Mitochondrial DNA Polymerase Thumb Subdomain Impart Severe Defects in Mitochondrial DNA Replication

Por Kasiviswanathan, Rajesh, Longley, Matthew J., Chan, Sherine S. L., Copeland, William C.
Publicado em 2009

PURIFICATION AND FUNCTIONAL CHARACTERIZATION OF HUMAN MITOCHONDRIAL DNA POLYMERASE GAMMA HARBORING DISEASE MUTATIONS

Por Kasiviswanathan, Rajesh, Longley, Matthew J., Young, Matthew J., Copeland, William C.
Publicado em 2010

Disease Variants of the Human Mitochondrial DNA Helicase Encoded by C10orf2 Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity

Por Longley, Matthew J., Humble, Margaret M., Sharief, Farida S., Copeland, William C.
Publicado em 2010

Long Patch Base Excision Repair in Mammalian Mitochondrial Genomes

Por Szczesny, Bartosz, Tann, Anne W., Longley, Matthew J., Copeland, William C., Mitra, Sankar
Publicado em 2008

Synergistic Effects of the in cis T251I and P587L Mitochondrial DNA Polymerase γ Disease Mutations

Por DeBalsi, Karen L., Longley, Matthew J., Hoff, Kirsten E., Copeland, William C.
Publicado no J Biol Chem (2017)

Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro

Por Longley, Matthew J., Prasad, Rajendra, Srivastava, Deepak K., Wilson, Samuel H., Copeland, William C.
Publicado em 1998

Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

Por Prasad, Rajendra, Longley, Matthew J., Sharief, Farida S., Hou, Esther W., Copeland, William C., Wilson, Samuel H.
Publicado em 2009

DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity

Por Song, Shiwei, Pursell, Zachary F., Copeland, William C., Longley, Matthew J., Kunkel, Thomas A., Mathews, Christopher K.
Publicado em 2005

Biochemical analysis of human POLG2 variants associated with mitochondrial disease

Por Young, Matthew J., Longley, Matthew J., Li, Fang-Yuan, Kasiviswanathan, Rajesh, Wong, Lee-Jun, Copeland, William C.
Publicado em 2011

POS5 Gene of Saccharomyces cerevisiae Encodes a Mitochondrial NADH Kinase Required for Stability of Mitochondrial DNA

Por Strand, Micheline K., Stuart, Gregory R., Longley, Matthew J., Graziewicz, Maria A., Dominick, Olivia C., Copeland, William C.
Publicado em 2003

A p.R369G POLG2 mutation associated with adPEO and multiple mtDNA deletions causes decreased affinity between polymerase γ subunits

Por Craig, Kate, Young, Matthew J., Blakely, Emma L., Longley, Matthew J., Turnbull, Douglass M., Copeland, William C., Taylor, Robert W.
Publicado em 2011

Mutant POLG2 Disrupts DNA Polymerase γ Subunits and Causes Progressive External Ophthalmoplegia

Por Longley, Matthew J., Clark, Susanna, Yu Wai Man, Cynthia, Hudson, Gavin, Durham, Steve E., Taylor, Robert W., Nightingale, Simon, Turnbull, Douglass M., Copeland, William C., Chinnery, Patrick F.
Publicado em 2006

Progressive External Ophthalmoplegia and Vision and Hearing Loss in a Patient With Mutations in POLG2 and OPA1

Por Ferraris, Silvio, Clark, Susanna, Garelli, Emanuela, Davidzon, Guido, Moore, Steven A., Kardon, Randy H., Bienstock, Rachelle J., Longley, Matthew J., Mancuso, Michelangelo, Ríos, Purificación Gutiérrez, Hirano, Michio, Copeland, William C., DiMauro, Salvatore
Publicado em 2008