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Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro

Mitochondria have been proposed to possess base excision repair processes to correct oxidative damage to the mitochondrial genome. As the only DNA polymerase (pol) present in mitochondria, pol γ is necessarily implicated in such processes. Therefore, we tested the ability of the catalytic subunit of...

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Detalhes bibliográficos
Main Authors: Longley, Matthew J., Prasad, Rajendra, Srivastava, Deepak K., Wilson, Samuel H., Copeland, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22816/
https://ncbi.nlm.nih.gov/pubmed/9770471
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