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DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair

Mutations in mitochondrial DNA (mtDNA) are associated with aging, and they can cause tissue degeneration and neuromuscular pathologies known as mitochondrial diseases. Because DNA polymerase γ (pol γ) is the enzyme responsible for replication and repair of mitochondrial DNA, the burden of faithful d...

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Detalles Bibliográficos
Publicado en:ScientificWorldJournal
Main Authors: Copeland, William C., Longley, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado: TheScientificWorldJOURNAL 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974855/
https://ncbi.nlm.nih.gov/pubmed/12806118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2003.09
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