Excision of Latent HIV-1 from Infected Cells In Vivo: An Important Step Forward

di De Silva Feelixge, Harshana S., Jerome, Keith R.
Pubblicato in Mol Ther (2017)

CELL AND GENE THERAPY STRATEGIES TO ERADICATE HIV RESERVOIRS

di Spragg, Chelsea, De Silva Feelixge, Harshana, Jerome, Keith R.
Pubblicato in Curr Opin HIV AIDS (2016)

CRISPR/Cas9 and Genome Editing for Viral Disease - Is Resistance Futile?

di De Silva Feelixge, Harshana S, Stone, Daniel, Roychoudhury, Pavitra, Aubert, Martine, Jerome, Keith R
Pubblicato in ACS Infect Dis (2018)

Pharmacodynamics of anti-HIV gene therapy using viral vectors and targeted endonucleases

di Roychoudhury, Pavitra, De Silva Feelixge, Harshana S., Pietz, Harlan L., Stone, Daniel, Jerome, Keith R., Schiffer, Joshua T.
Pubblicato in J Antimicrob Chemother (2016)

Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir

di Roychoudhury, Pavitra, De Silva Feelixge, Harshana, Reeves, Daniel, Mayer, Bryan T., Stone, Daniel, Schiffer, Joshua T., Jerome, Keith R.
Pubblicato in BMC Biol (2018)

AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication

di Weber, Nicholas D., Stone, Daniel, Sedlak, Ruth Hall, De Silva Feelixge, Harshana S., Roychoudhury, Pavitra, Schiffer, Joshua T., Aubert, Martine, Jerome, Keith R.
Pubblicazione 2014

Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy

di De Silva Feelixge, Harshana S., Stone, Daniel, Pietz, Harlan L., Roychoudhury, Pavitra, Greninger, Alex L., Schiffer, Joshua T., Aubert, Martine, Jerome, Keith R.
Pubblicato in Antiviral Res (2015)

In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia

di Dang, Chung H., Aubert, Martine, De Silva Feelixge, Harshana S., Diem, Kurt, Loprieno, Michelle A., Roychoudhury, Pavitra, Stone, Daniel, Jerome, Keith R.
Pubblicato in Sci Rep (2017)

Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses

di Niyonzima, Nixon, Lambert, Abigail R., Werther, Rachel, De Silva Feelixge, Harshana, Roychoudhury, Pavitra, Greninger, Alexander L., Stone, Daniel, Stoddard, Barry L., Jerome, Keith R.
Pubblicato in Protein Eng Des Sel (2017)

Digital detection of endonuclease mediated gene disruption in the HIV provirus

di Sedlak, Ruth Hall, Liang, Shu, Niyonzima, Nixon, De Silva Feelixge, Harshana S., Roychoudhury, Pavitra, Greninger, Alexander L., Weber, Nicholas D., Boissel, Sandrine, Scharenberg, Andrew M., Cheng, Anqi, Magaret, Amalia, Bumgarner, Roger, Stone, Daniel, Jerome, Keith R.
Pubblicato in Sci Rep (2016)

Gene editing and elimination of latent herpes simplex virus in vivo

di Aubert, Martine, Strongin, Daniel E., Roychoudhury, Pavitra, Loprieno, Michelle A., Haick, Anoria K., Klouser, Lindsay M., Stensland, Laurence, Huang, Meei-Li, Makhsous, Negar, Tait, Alexander, De Silva Feelixge, Harshana S., Galetto, Roman, Duchateau, Philippe, Greninger, Alexander L., Stone, Daniel, Jerome, Keith R.
Pubblicato in Nat Commun (2020)

Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors

di Stone, Daniel, Kenkel, Elizabeth J., Loprieno, Michelle A., Tanaka, Motoko, De Silva Feelixge, Harshana S., Kumar, Arjun J., Stensland, Laurence, Obenza, Willimark M., Wangari, Solomon, Ahrens, Chul Y., Murnane, Robert D., Peterson, Christopher W., Kiem, Hans-Peter, Huang, Meei-Li, Aubert, Martine, Hu, Shiu-Lok, Jerome, Keith R.
Pubblicato in Hum Gene Ther (2021)

CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice

di Stone, Daniel, Long, Kelly R., Loprieno, Michelle A., De Silva Feelixge, Harshana S., Kenkel, Elizabeth J., Liley, R. Matt, Rapp, Stephen, Roychoudhury, Pavitra, Nguyen, Thuy, Stensland, Laurence, Colón-Thillet, Rossana, Klouser, Lindsay M., Weber, Nicholas D., Le, Connie, Wagoner, Jessica, Goecker, Erin A., Li, Alvason Zhenhua, Eichholz, Karsten, Corey, Lawrence, Tyrrell, D. Lorne, Greninger, Alexander L., Huang, Meei-Li, Polyak, Stephen J., Aubert, Martine, Sagartz, John E., Jerome, Keith R.
Pubblicato in Mol Ther Methods Clin Dev (2020)