Digital detection of endonuclease mediated gene disruption in the HIV provirus

Genome editing by designer nucleases is a rapidly evolving technology utilized in a highly diverse set of research fields. Among all fields, the T7 endonuclease mismatch cleavage assay, or Surveyor assay, is the most commonly used tool to assess genomic editing by designer nucleases. This assay, whi...

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Vydáno v:Sci Rep
Hlavní autoři: Sedlak, Ruth Hall, Liang, Shu, Niyonzima, Nixon, De Silva Feelixge, Harshana S., Roychoudhury, Pavitra, Greninger, Alexander L., Weber, Nicholas D., Boissel, Sandrine, Scharenberg, Andrew M., Cheng, Anqi, Magaret, Amalia, Bumgarner, Roger, Stone, Daniel, Jerome, Keith R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735761/
https://ncbi.nlm.nih.gov/pubmed/26829887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20064
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