Pharmacodynamics of anti-HIV gene therapy using viral vectors and targeted endonucleases

OBJECTIVES: A promising curative approach for HIV is to use designer endonucleases that bind and cleave specific target sequences within latent genomes, resulting in mutations that render the virus replication incompetent. We developed a mathematical model to describe the expression and activity of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Antimicrob Chemother
Main Authors: Roychoudhury, Pavitra, De Silva Feelixge, Harshana S., Pietz, Harlan L., Stone, Daniel, Jerome, Keith R., Schiffer, Joshua T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954920/
https://ncbi.nlm.nih.gov/pubmed/27090632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw104
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker