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Pharmacodynamics of anti-HIV gene therapy using viral vectors and targeted endonucleases
OBJECTIVES: A promising curative approach for HIV is to use designer endonucleases that bind and cleave specific target sequences within latent genomes, resulting in mutations that render the virus replication incompetent. We developed a mathematical model to describe the expression and activity of...
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| Publicado no: | J Antimicrob Chemother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4954920/ https://ncbi.nlm.nih.gov/pubmed/27090632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw104 |
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