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In vivo disruption of latent HSV by designer endonuclease therapy

A large portion of the global population carries latent herpes simplex virus (HSV), which can periodically reactivate, resulting in asymptomatic shedding or formation of ulcerative lesions. Current anti-HSV drugs do not eliminate latent virus from sensory neurons where HSV resides, and therefore do...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Aubert, Martine, Madden, Emily A., Loprieno, Michelle, Feelixge, Harshana S. DeSilva, Stensland, Laurence, Huang, Meei-Li, Greninger, Alexander L., Roychoudhury, Pavitra, Niyonzima, Nixon, Nguyen, Thuy, Magaret, Amalia, Galleto, Roman, Stone, Daniel, Jerome, Keith R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026126/
https://ncbi.nlm.nih.gov/pubmed/27642635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88468
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