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In vivo disruption of latent HSV by designer endonuclease therapy

A large portion of the global population carries latent herpes simplex virus (HSV), which can periodically reactivate, resulting in asymptomatic shedding or formation of ulcerative lesions. Current anti-HSV drugs do not eliminate latent virus from sensory neurons where HSV resides, and therefore do...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Aubert, Martine, Madden, Emily A., Loprieno, Michelle, Feelixge, Harshana S. DeSilva, Stensland, Laurence, Huang, Meei-Li, Greninger, Alexander L., Roychoudhury, Pavitra, Niyonzima, Nixon, Nguyen, Thuy, Magaret, Amalia, Galleto, Roman, Stone, Daniel, Jerome, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026126/
https://ncbi.nlm.nih.gov/pubmed/27642635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88468
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