A role for proapoptotic Bax and Bak in T-cell differentiation and transformation

Por Biswas, Subhrajit, Shi, Qiong, Matise, Lauren, Cleveland, Susan, Dave, Utpal, Zinkel, Sandra
Publicado em 2010

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease

Por Ye, Jin, Davé, Utpal P., Grishin, Nick V., Goldstein, Joseph L., Brown, Michael S.
Publicado em 2000

LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding

Por Layer, Justin H., Alford, Catherine E., McDonald, W. Hayes, Davé, Utpal P.
Publicado no Mol Cell Biol (2016)

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Por Elliott, Natalina E., Cleveland, Susan M., Grann, Victor, Janik, John, Waldmann, Thomas A., Davé, Utpal P.
Publicado em 2011

Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias

Por Goodings, Charnise, Tripathi, Rati, Cleveland, Susan M., Elliott, Natalina, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publicado no Leuk Res (2014)

Experiences Building Globus Genomics: A Next-Generation Sequencing Analysis Service using Galaxy, Globus, and Amazon Web Services

Por Madduri, Ravi K., Sulakhe, Dinanath, Lacinski, Lukasz, Liu, Bo, Rodriguez, Alex, Chard, Kyle, Dave, Utpal J., Foster, Ian T.
Publicado em 2014

Tgif1 Regulates Quiescence and Self-Renewal of Hematopoietic Stem Cells

Por Yan, Ling, Womack, Bethany, Wotton, David, Guo, Yan, Shyr, Yu, Davé, Utpal, Li, Chun, Hiebert, Scott, Brandt, Stephen, Hamid, Rizwan
Publicado em 2013

Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses

Por Liu, Bo, Madduri, Ravi K, Sotomayor, Borja, Chard, Kyle, Lacinski, Lukasz, Dave, Utpal J, Li, Jianqiang, Liu, Chunchen, Foster, Ian T
Publicado em 2014

LIM domain only-2 (Lmo2) induces T-cell leukemia with epigenetic deregulation of CD4

Por Cleveland, Susan M., Goodings, Charnise, Tripathi, Rati M., Elliott, Natalina, Thompson, Mary Ann, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publicado no Exp Hematol (2014)

A case study for cloud based high throughput analysis of NGS data using the globus genomics system

Por Bhuvaneshwar, Krithika, Sulakhe, Dinanath, Gauba, Robinder, Rodriguez, Alex, Madduri, Ravi, Dave, Utpal, Lacinski, Lukasz, Foster, Ian, Gusev, Yuriy, Madhavan, Subha
Publicado no Comput Struct Biotechnol J (2014)

Lynx web services for annotations and systems analysis of multi-gene disorders

Por Sulakhe, Dinanath, Taylor, Andrew, Balasubramanian, Sandhya, Feng, Bo, Xie, Bingqing, Börnigen, Daniela, Dave, Utpal J., Foster, Ian T., Gilliam, T. Conrad, Maltsev, Natalia
Publicado em 2014

Lynx: a database and knowledge extraction engine for integrative medicine

Por Sulakhe, Dinanath, Balasubramanian, Sandhya, Xie, Bingqing, Feng, Bo, Taylor, Andrew, Wang, Sheng, Berrocal, Eduardo, Dave, Utpal, Xu, Jinbo, Börnigen, Daniela, Gilliam, T. Conrad, Maltsev, Natalia
Publicado em 2014

Murine Leukemias with Retroviral Insertions at Lmo2 Are Predictive of the Leukemias Induced in SCID-X1 Patients Following Retroviral Gene Therapy

Por Davé, Utpal P., Akagi, Keiko, Tripathi, Rati, Cleveland, Susan M., Thompson, Mary A., Yi, Ming, Stephens, Robert, Downing, James R., Jenkins, Nancy A., Copeland, Neal G.
Publicado em 2009

Lynx: a knowledge base and an analytical workbench for integrative medicine

Por Sulakhe, Dinanath, Xie, Bingqing, Taylor, Andrew, D'Souza, Mark, Balasubramanian, Sandhya, Hashemifar, Somaye, White, Steven, Dave, Utpal J., Agam, Gady, Xu, Jinbo, Wang, Sheng, Gilliam, T. Conrad, Maltsev, Natalia
Publicado no Nucleic Acids Res (2016)

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

Por Aue, Georg, Du, Yang, Cleveland, Susan M., Smith, Stephen B., Davé, Utpal P., Liu, Delong, Weniger, Marc A., Metais, Jean Yves, Jenkins, Nancy A., Copeland, Neal G., Dunbar, Cynthia E.
Publicado em 2011

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides

Por McGirt, Laura Y., Jia, Peilin, Baerenwald, Devin A., Duszynski, Robert J., Dahlman, Kimberly B., Zic, John A., Zwerner, Jeffrey P., Hucks, Donald, Dave, Utpal, Zhao, Zhongming, Eischen, Christine M.
Publicado no Blood (2015)

Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation

Por Goodings, Charnise, Smith, Elizabeth, Mathias, Elizabeth, Elliott, Natalina, Cleveland, Susan M., Tripathi, Rati M., Layer, Justin H., Chen, Xi, Guo, Yan, Shyr, Yu, Hamid, Rizwan, Du, Yang, Davé, Utpal P.
Publicado no Stem Cells (2015)

Lmo2 induces hematopoietic stem cell like features in T-cell progenitor cells prior to leukemia

Por Cleveland, Susan M., Smith, Stephen, Tripathi, Rati, Mathias, Elizabeth M., Goodings, Charnise, Elliott, Natalina, Peng, Dunfa, El-Rifai, Wael, Yi, Dajun, Chen, Xi, Li, Liqi, Mullighan, Charles, Downing, James R., Love, Paul, Davé, Utpal P.
Publicado em 2013

Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation

Por Triplett, Todd A., Cardenas, Kim T., Lancaster, Jessica N., Hu, Zicheng, Selden, Hilary J., Jasso, Guadalupe J., Balasubramanyam, Sadhana, Chan, Kathy, Li, LiQi, Chen, Xi, Marcogliese, Andrea N., Davé, Utpal P., Love, Paul E., Ehrlich, Lauren I. R.
Publicado no Proc Natl Acad Sci U S A (2016)

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways

Por Smith, Stephen, Tripathi, Rati, Goodings, Charnise, Cleveland, Susan, Mathias, Elizabeth, Hardaway, J. Andrew, Elliott, Natalina, Yi, Yajun, Chen, Xi, Downing, James, Mullighan, Charles, Swing, Deborah A., Tessarollo, Lino, Li, Liqi, Love, Paul, Jenkins, Nancy A., Copeland, Neal G., Thompson, Mary Ann, Du, Yang, Davé, Utpal P.
Publicado em 2014