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Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias

LIM domain Only-2 (LMO2) overexpression in T cells induces leukemia but the molecular mechanism remains to be elucidated. In hematopoietic stem and progenitor cells, Lmo2 is part of a protein complex comprised of class II basic helix loop helix proteins, Tal1and Lyl1. The latter transcription factor...

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Detalhes bibliográficos
Publicado no:Leuk Res
Main Authors: Goodings, Charnise, Tripathi, Rati, Cleveland, Susan M., Elliott, Natalina, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277943/
https://ncbi.nlm.nih.gov/pubmed/25499232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2014.11.016
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