AAV Joins the Rank of Genotoxic Vectors

Por Davé, Utpal P., Cornetta, Kenneth
Publicado no Mol Ther (2021)

Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia

Por Yan, Ling, Davé, Utpal P., Engel, Michael, Brandt, Stephen J., Hamid, Rizwan
Publicado no J Cell Mol Med (2020)

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease

Por Ye, Jin, Davé, Utpal P., Grishin, Nick V., Goldstein, Joseph L., Brown, Michael S.
Publicado em 2000

LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding

Por Layer, Justin H., Alford, Catherine E., McDonald, W. Hayes, Davé, Utpal P.
Publicado no Mol Cell Biol (2016)

LDB1 Enforces Stability on Direct and Indirect Oncoprotein Partners in Leukemia

Por Layer, Justin H., Christy, Michael, Placek, Lindsey, Unutmaz, Derya, Guo, Yan, Davé, Utpal P.
Publicado no Mol Cell Biol (2020)

FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

Por Elliott, Natalina E., Cleveland, Susan M., Grann, Victor, Janik, John, Waldmann, Thomas A., Davé, Utpal P.
Publicado em 2011

Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias

Por Goodings, Charnise, Tripathi, Rati, Cleveland, Susan M., Elliott, Natalina, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publicado no Leuk Res (2014)

LIM domain only-2 (Lmo2) induces T-cell leukemia with epigenetic deregulation of CD4

Por Cleveland, Susan M., Goodings, Charnise, Tripathi, Rati M., Elliott, Natalina, Thompson, Mary Ann, Guo, Yan, Shyr, Yu, Davé, Utpal P.
Publicado no Exp Hematol (2014)

Murine Leukemias with Retroviral Insertions at Lmo2 Are Predictive of the Leukemias Induced in SCID-X1 Patients Following Retroviral Gene Therapy

Por Davé, Utpal P., Akagi, Keiko, Tripathi, Rati, Cleveland, Susan M., Thompson, Mary A., Yi, Ming, Stephens, Robert, Downing, James R., Jenkins, Nancy A., Copeland, Neal G.
Publicado em 2009

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

Por Aue, Georg, Du, Yang, Cleveland, Susan M., Smith, Stephen B., Davé, Utpal P., Liu, Delong, Weniger, Marc A., Metais, Jean Yves, Jenkins, Nancy A., Copeland, Neal G., Dunbar, Cynthia E.
Publicado em 2011

Hhex is Required at Multiple Stages of Adult Hematopoietic Stem and Progenitor Cell Differentiation

Por Goodings, Charnise, Smith, Elizabeth, Mathias, Elizabeth, Elliott, Natalina, Cleveland, Susan M., Tripathi, Rati M., Layer, Justin H., Chen, Xi, Guo, Yan, Shyr, Yu, Hamid, Rizwan, Du, Yang, Davé, Utpal P.
Publicado no Stem Cells (2015)

Lmo2 induces hematopoietic stem cell like features in T-cell progenitor cells prior to leukemia

Por Cleveland, Susan M., Smith, Stephen, Tripathi, Rati, Mathias, Elizabeth M., Goodings, Charnise, Elliott, Natalina, Peng, Dunfa, El-Rifai, Wael, Yi, Dajun, Chen, Xi, Li, Liqi, Mullighan, Charles, Downing, James R., Love, Paul, Davé, Utpal P.
Publicado em 2013

Ldb1 is required for Lmo2 oncogene–induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia

Por Li, LiQi, Mitra, Apratim, Cui, Kairong, Zhao, Bin, Choi, Seeyoung, Lee, Jan Y., Stamos, Daniel B., El-Khoury, Dalal, Warzecha, Claude, Pfeifer, Karl, Hardwick, Joyce, Zhao, Keji, Venters, Bryan, Davé, Utpal P., Love, Paul E.
Publicado no Blood (2020)

Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted Therapies

Por Greenplate, Allison, Wang, Kai, Tripathi, Rati M., Palma, Norma, Ali, Siraj M., Stephens, Phil J., Miller, Vincent A., Shyr, Yu, Guo, Yan, Reddy, Nishitha M., Kozhaya, Lina, Unutmaz, Derya, Chen, Xueyan, Irish, Jonathan M., Davé, Utpal P.
Publicado no JCO Precis Oncol (2018)

Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation

Por Triplett, Todd A., Cardenas, Kim T., Lancaster, Jessica N., Hu, Zicheng, Selden, Hilary J., Jasso, Guadalupe J., Balasubramanyam, Sadhana, Chan, Kathy, Li, LiQi, Chen, Xi, Marcogliese, Andrea N., Davé, Utpal P., Love, Paul E., Ehrlich, Lauren I. R.
Publicado no Proc Natl Acad Sci U S A (2016)

PI3Kγ/δ and NOTCH1 cross-regulate pathways that define the T-cell acute lymphoblastic leukemia disease signature

Por Efimenko, Evgeni, Davé, Utpal P., Lebedeva, Irina V., Shen, Yao, Sanchez-Quintero, Maria J., Diolaiti, Daniel, Kung, Andrew, Lannutti, Brian J., Chen, Jianchung, Realubit, Ronald, Niatsetskiya, Zoya, Ten, Vadim, Karan, Charles, Chen, Xi, Califano, Andrea, Diacovo, Thomas G.
Publicado no Mol Cancer Ther (2017)

LIM Domain Only-2 (LMO2) Induces T-Cell Leukemia by Two Distinct Pathways

Por Smith, Stephen, Tripathi, Rati, Goodings, Charnise, Cleveland, Susan, Mathias, Elizabeth, Hardaway, J. Andrew, Elliott, Natalina, Yi, Yajun, Chen, Xi, Downing, James, Mullighan, Charles, Swing, Deborah A., Tessarollo, Lino, Li, Liqi, Love, Paul, Jenkins, Nancy A., Copeland, Neal G., Thompson, Mary Ann, Du, Yang, Davé, Utpal P.
Publicado em 2014

Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

Por Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea
Publicado no Nat Commun (2020)

Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

Por Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea
Publicado no Nat Commun (2020)

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia

Por Roels, Juliette, Thénoz, Morgan, Szarzyńska, Bronisława, Landfors, Mattias, De Coninck, Stien, Demoen, Lisa, Provez, Lien, Kuchmiy, Anna, Strubbe, Steven, Reunes, Lindy, Pieters, Tim, Matthijssens, Filip, Van Loocke, Wouter, Erarslan-Uysal, Büşra, Richter-Pechańska, Paulina, Declerck, Ken, Lammens, Tim, De Moerloose, Barbara, Deforce, Dieter, Van Nieuwerburgh, Filip, Cheung, Laurence C., Kotecha, Rishi S., Mansour, Marc R., Ghesquière, Bart, Van Camp, Guy, Berghe, Wim Vanden, Kowalczyk, Jerzy R., Szczepański, Tomasz, Davé, Utpal P., Kulozik, Andreas E., Goossens, Steven, Curtis, David J., Taghon, Tom, Dawidowska, Małgorzata, Degerman, Sofie, Van Vlierberghe, Pieter
Publicado no Blood Cancer Discov (2020)