Application of high-throughput screening to identify a novel αIIb-specific small- molecule inhibitor of αIIbβ3-mediated platelet interaction with fibrinogen

Por Blue, Robert, Murcia, Marta, Karan, Charles, Jiroušková, Markéta, Coller, Barry S.
Publicado em 2008

TSH Receptor Signaling Abrogation by a Novel Small Molecule

Por Latif, Rauf, Realubit, Ronald B., Karan, Charles, Mezei, Mihaly, Davies, Terry F.
Publicado no Front Endocrinol (Lausanne) (2016)

A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient

Por Chang, Jeremy B., Quinnies, Kayla M., Realubit, Ronald, Karan, Charles, Rand, Jacob H., Tatonetti, Nicholas P.
Publicado no Sci Rep (2016)

ET-57 TOPOISOMERASE II IN PRONEURAL GLIOMAS, A MODULATOR OF TRANSCRIPTION AND A THERAPEUTIC TARGET

Por Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Praver, Moshe, Realubit, Ronald, Li, Hai, Karan, Charles, Banu, Matei, Lei, Liang, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey
Publicado em 2014

Elucidating Compound Mechanism of Action by Network Perturbation Analysis

Por Woo, Jung Hoon, Shimoni, Yishai, Yang, Wan Seok, Subramaniam, Prem, Iyer, Archana, Nicoletti, Paola, Martínez, María Rodríguez, López, Gonzalo, Mattioli, Michela, Realubit, Ronald, Karan, Charles, Stockwell, Brent R., Bansal, Mukesh, Califano, Andrea
Publicado no Cell (2015)

Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma

Por Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Leung, Richard, Lei, Liang, Realubit, Ronald, Li, Hai, Karan, Charles, Yun, Jonathan, Showers, Christopher, Rothcock, Robert, O, Jane, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey N.
Publicado em 2014

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies

Por Deng, Changchun, Lipstein, Mark R., Scotto, Luigi, Jirau Serrano, Xavier O., Mangone, Michael A., Li, Shirong, Vendome, Jeremie, Hao, Yun, Xu, Xiaoming, Deng, Shi-Xian, Realubit, Ronald B., Tatonetti, Nicholas P., Karan, Charles, Lentzsch, Suzanne, Fruman, David A., Honig, Barry, Landry, Donald W., O’Connor, Owen A.
Publicado no Blood (2017)

A community computational challenge to predict the activity of pairs of compounds

Por Bansal, Mukesh, Yang, Jichen, Karan, Charles, Menden, Michael P, Costello, James C, Tang, Hao, Xiao, Guanghua, Li, Yajuan, Allen, Jeffrey, Zhong, Rui, Chen, Beibei, Kim, Minsoo, Wang, Tao, Heiser, Laura M, Realubit, Ronald, Mattioli, Michela, Alvarez, Mariano J, Shen, Yao, Gallahan, Daniel, Singer, Dinah, Saez-Rodriguez, Julio, Xie, Yang, Stolovitzky, Gustavo, Califano, Andrea
Publicado no Nat Biotechnol (2014)