ET-57 TOPOISOMERASE II IN PRONEURAL GLIOMAS, A MODULATOR OF TRANSCRIPTION AND A THERAPEUTIC TARGET

Topoisomerase II (TOP2) is highly expressed on proneural gliomas, but its specific function on these tumors is unknown. We found that TOP2 is expressed in gliomas from early stages, increases during progression, and is elevated in radiographically localized non-enhancing regions of human glioblastom...

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Detalhes bibliográficos
Main Authors: Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Praver, Moshe, Realubit, Ronald, Li, Hai, Karan, Charles, Banu, Matei, Lei, Liang, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218153/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.54
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