GENE-08. PHARMACOLOGIC MODULATION OF MYC AND PDGFRA BY TARGETING TOPOISOMERASE II ON GLIOMAS

Topoisomerase II (TOP2B) A/B regulate transcription by inducing double-strand DNA breaks and enhancing chromatin accessibility in other contexts, but their role in gliomas has not been elucidated. We investigated the effect of TOP2A/B on epigenetic regulation in glioma cell lines and explored the ta...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Gonzalez-Buendia, Edgar, Feldstein, Eric, Zhao, Junfei, Mahajan, Aayushi, Realubit, Ronald, Karan, Charles, Rabadan, Raul, Sonabend, Adam M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692837/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.383
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