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GENE-08. PHARMACOLOGIC MODULATION OF MYC AND PDGFRA BY TARGETING TOPOISOMERASE II ON GLIOMAS
Topoisomerase II (TOP2B) A/B regulate transcription by inducing double-strand DNA breaks and enhancing chromatin accessibility in other contexts, but their role in gliomas has not been elucidated. We investigated the effect of TOP2A/B on epigenetic regulation in glioma cell lines and explored the ta...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692837/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.383 |
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