GENE-17. TOP2B REGULATES CDK4 SPLICE VARIANTS IN GLIOMAS

Topoisomerase IIB (TOP2B) is known to decoil and decatenate DNA, releasing chromatin torsional forces. Whereas TOP2B has been implicated in transcript splicing, direct evidence supporting this function, through localization of TOP2B to specific chromatin sites and in association with specific types...

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Publicado no:Neuro Oncol
Main Authors: Gonzalez-Buendia, Edgar, Zhao, Junfei, Chen, Li, Feldstein, Eric, Mahajan, Aayushi, Rabadan, Raul, James, C David, Sonabend, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216622/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.443
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