Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma

BACKGROUND: Glioblastoma subtypes have been defined based on transcriptional profiling, yet personalized care based on molecular classification remains unexploited. Topoisomerase II (TOP2) contributes to the transcriptional signature of the proneural glioma subtype. Thus, we targeted TOP2 pharmacolo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Leung, Richard, Lei, Liang, Realubit, Ronald, Li, Hai, Karan, Charles, Yun, Jonathan, Showers, Christopher, Rothcock, Robert, O, Jane, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey N.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2014
נושאים:
Basic and Translational Investigations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136893/
https://ncbi.nlm.nih.gov/pubmed/24637229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou026
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