Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma

BACKGROUND: Glioblastoma subtypes have been defined based on transcriptional profiling, yet personalized care based on molecular classification remains unexploited. Topoisomerase II (TOP2) contributes to the transcriptional signature of the proneural glioma subtype. Thus, we targeted TOP2 pharmacolo...

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Detalhes bibliográficos
Main Authors: Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Leung, Richard, Lei, Liang, Realubit, Ronald, Li, Hai, Karan, Charles, Yun, Jonathan, Showers, Christopher, Rothcock, Robert, O, Jane, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136893/
https://ncbi.nlm.nih.gov/pubmed/24637229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou026
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