Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma

BACKGROUND: Glioblastoma subtypes have been defined based on transcriptional profiling, yet personalized care based on molecular classification remains unexploited. Topoisomerase II (TOP2) contributes to the transcriptional signature of the proneural glioma subtype. Thus, we targeted TOP2 pharmacolo...

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Detaylı Bibliyografya
Asıl Yazarlar: Sonabend, Adam M., Carminucci, Arthur S., Amendolara, Benjamin, Bansal, Mukesh, Leung, Richard, Lei, Liang, Realubit, Ronald, Li, Hai, Karan, Charles, Yun, Jonathan, Showers, Christopher, Rothcock, Robert, O, Jane, Califano, Andrea, Canoll, Peter, Bruce, Jeffrey N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Basic and Translational Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136893/
https://ncbi.nlm.nih.gov/pubmed/24637229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou026
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