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A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma

BACKGROUND: Mouse models of glioblastoma (GBM), the most aggressive primary brain tumor, are critical for understanding GBM pathology and can contribute to the preclinical evaluation of therapeutic agents. Platelet-derived growth factor (PDGF) signaling has been implicated in the development and pat...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rahme, Gilbert J, Luikart, Bryan W, Cheng, Chao, Israel, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817944/
https://ncbi.nlm.nih.gov/pubmed/29016807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox129
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