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The Probable Cell of Origin of NF1- and PDGF-Driven Glioblastomas

Primary glioblastomas are subdivided into several molecular subtypes. There is an ongoing debate over the cell of origin for these tumor types where some suggest a progenitor while others argue for a stem cell origin. Even within the same molecular subgroup, and using lineage tracing in mouse models...

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Detalhes bibliográficos
Main Authors: Hambardzumyan, Dolores, Cheng, Yu-Kang, Haeno, Hiroshi, Holland, Eric C., Michor, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170338/
https://ncbi.nlm.nih.gov/pubmed/21931722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024454
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