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A progenitor cell origin of myeloid malignancies
All cancers rely on cells that have properties of long-term self-renewal or “stemness” to maintain and propagate the tumor, but the cell of origin of most cancers is still unknown. Here, we design a stochastic mathematical model of hematopoietic stem and progenitor cells to study the evolutionary dy...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757818/ https://ncbi.nlm.nih.gov/pubmed/19805346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908107106 |
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