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Mathematical Modeling of PDGF-Driven Glioblastoma Reveals Optimized Radiation Dosing Schedules

Glioblastomas (GBMs) are the most common and malignant primary brain tumors and are aggressively treated with surgery, chemotherapy, and radiotherapy. Despite this treatment, recurrence is inevitable and survival has improved minimally over the last 50 years. Recent studies have suggested that GBMs...

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Bibliografiske detaljer
Main Authors: Leder, Kevin, Pitter, Ken, LaPlant, Quincey, Hambardzumyan, Dolores, Ross, Brian D., Chan, Timothy A., Holland, Eric C., Michor, Franziska
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923371/
https://ncbi.nlm.nih.gov/pubmed/24485463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.12.029
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