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CS-19 PDGF SIGNALING DEPENDENCE IN PRONEURAL GLIOBLASTOMA, THE BEGINNING BUT NOT THE END

Proneural glioblastoma (GBM) is characterized by PDGF signaling through receptor and/or ligand overexpression or amplification. Despite this, clinical trials using the tyrosine kinase receptor inhibitor Gleveec for GBM have failed. The inability to respond to PDGFR inhibition could either be at the...

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Detaylı Bibliyografya
Asıl Yazarlar: Lindberg, Nanna, Kim, Youngmi, Halliday, John, Pitter, Ken, Holland, Eric C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217975/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou242.19
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