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TSH Receptor Signaling Abrogation by a Novel Small Molecule
Pathological activation of the thyroid-stimulating hormone receptor (TSHR) is caused by thyroid-stimulating antibodies in patients with Graves’ disease (GD) or by somatic and rare genomic mutations that enhance constitutive activation of the receptor influencing both G protein and non-G protein sign...
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| Publicat a: | Front Endocrinol (Lausanne) |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037132/ https://ncbi.nlm.nih.gov/pubmed/27729899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00130 |
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