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TSH Receptor Signaling Abrogation by a Novel Small Molecule
Pathological activation of the thyroid-stimulating hormone receptor (TSHR) is caused by thyroid-stimulating antibodies in patients with Graves’ disease (GD) or by somatic and rare genomic mutations that enhance constitutive activation of the receptor influencing both G protein and non-G protein sign...
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| Publicado no: | Front Endocrinol (Lausanne) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037132/ https://ncbi.nlm.nih.gov/pubmed/27729899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00130 |
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