The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

To gain further insight into the binding of the normal and variant human TSHβ subunits (TSHβ and TSHβv), we modeled the 2 monomeric proteins and studied their interaction with the TSH receptor ectodomain (TSHR-ECD) using molecular dynamics simulation Furthermore, analyzed their bioactivity in vitro...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: Mezei, Mihaly, Baliram, Ramkumarie, Ali, M Rejwan, Zaidi, Mone, Davies, Terry F, Latif, Rauf
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447003/
https://ncbi.nlm.nih.gov/pubmed/32738139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa125
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