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The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

To gain further insight into the binding of the normal and variant human TSHβ subunits (TSHβ and TSHβv), we modeled the 2 monomeric proteins and studied their interaction with the TSH receptor ectodomain (TSHR-ECD) using molecular dynamics simulation Furthermore, analyzed their bioactivity in vitro...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Mezei, Mihaly, Baliram, Ramkumarie, Ali, M Rejwan, Zaidi, Mone, Davies, Terry F, Latif, Rauf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447003/
https://ncbi.nlm.nih.gov/pubmed/32738139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa125
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