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The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

To gain further insight into the binding of the normal and variant human TSHβ subunits (TSHβ and TSHβv), we modeled the 2 monomeric proteins and studied their interaction with the TSH receptor ectodomain (TSHR-ECD) using molecular dynamics simulation Furthermore, analyzed their bioactivity in vitro...

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Bibliografski detalji
Izdano u:Endocrinology
Glavni autori: Mezei, Mihaly, Baliram, Ramkumarie, Ali, M Rejwan, Zaidi, Mone, Davies, Terry F, Latif, Rauf
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447003/
https://ncbi.nlm.nih.gov/pubmed/32738139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa125
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