The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

To gain further insight into the binding of the normal and variant human TSHβ subunits (TSHβ and TSHβv), we modeled the 2 monomeric proteins and studied their interaction with the TSH receptor ectodomain (TSHR-ECD) using molecular dynamics simulation Furthermore, analyzed their bioactivity in vitro...

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Gepubliceerd in:Endocrinology
Hoofdauteurs: Mezei, Mihaly, Baliram, Ramkumarie, Ali, M Rejwan, Zaidi, Mone, Davies, Terry F, Latif, Rauf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447003/
https://ncbi.nlm.nih.gov/pubmed/32738139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa125
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