The Human TSHβ Subunit Proteins and Their Binding Sites on the TSH Receptor Using Molecular Dynamics Simulation

To gain further insight into the binding of the normal and variant human TSHβ subunits (TSHβ and TSHβv), we modeled the 2 monomeric proteins and studied their interaction with the TSH receptor ectodomain (TSHR-ECD) using molecular dynamics simulation Furthermore, analyzed their bioactivity in vitro...

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Опубликовано в: :Endocrinology
Главные авторы: Mezei, Mihaly, Baliram, Ramkumarie, Ali, M Rejwan, Zaidi, Mone, Davies, Terry F, Latif, Rauf
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447003/
https://ncbi.nlm.nih.gov/pubmed/32738139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa125
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