Elucidating Compound Mechanism of Action by Network Perturbation Analysis

Genome-wide identification of the mechanism of action (MoA) of small-molecule compounds characterizing their targets, effectors, and activity modulators, represents a highly relevant yet elusive goal, with critical implications for assessment of compound efficacy and toxicity. Current approaches are...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Woo, Jung Hoon, Shimoni, Yishai, Yang, Wan Seok, Subramaniam, Prem, Iyer, Archana, Nicoletti, Paola, Martínez, María Rodríguez, López, Gonzalo, Mattioli, Michela, Realubit, Ronald, Karan, Charles, Stockwell, Brent R., Bansal, Mukesh, Califano, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506491/
https://ncbi.nlm.nih.gov/pubmed/26186195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.056
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