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Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase

[Image: see text] Compound libraries provide a starting point for multiple biological investigations, but the structural integrity of compounds is rarely assessed experimentally until a late stage in the research process. Here, we describe the discovery of a neuroprotective small molecule that was o...

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Pubblicato in:ACS Med Chem Lett
Autori principali: Kaplan, Anna, Stockwell, Brent R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603724/
https://ncbi.nlm.nih.gov/pubmed/26500720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00014
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