Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

To understand drug combination effect, it is necessary to decipher the interactions between drug targets—many of which are signaling molecules. Previously, such signaling pathway models are largely based on the compilation of literature data from heterogeneous cellular contexts. Indeed, de novo reco...

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Udgivet i:PLoS One
Main Authors: Bansal, Mukesh, He, Jing, Peyton, Michael, Kustagi, Manjunath, Iyer, Archana, Comb, Michael, White, Michael, Minna, John D., Califano, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322741/
https://ncbi.nlm.nih.gov/pubmed/30615629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208646
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